The work is controversial because it showed that scientists could manipulate life in its earliest stages and that those changes would then be inherited by future generations, if the embryo were allowed to grow into a baby. (The embryo in question was destroyed.) It also raised the tantalizing promise that the baby would be disease-free and would not transmit the disease to his or her descendants. The work, a collaboration by the Salk Institute, Oregon Health and Science University and Korea’s Institute for Basic Science, was performed using private money since the United States forbids the use of federal funds for embryo research. But it raises a host of ethical questions with religious ramifications.